Endocrine Abstracts

The frequency of adrenal masses is increasing in parallel with the progress of the technology. Most of these masses, which are detected by chance, are not functional, and only a part of them are exposed to an excess of hormone. The most common dysfunction in masses with hormonal activity is hypercortisolism. However, the diagnosis of Cushing’s disease is based on more than one test. In this study, we intended to compare the values of screening tests to determine whether t...

Aim: Patients with hypoparatiroidism may admit to hospitals with different symptoms.In this report we presented 3 case of hypoparatiroidism with congestive heart failure,epilepsy and muscle pain.Case 1: 31-year-old male admitted to hospital with dyspnea on lying down and evaluation revealed pericardial and pleural effusion. The patient was hospitalized to cardiology clinic with a prediagnosis of decompansated heart failure. In echocardiography ejection f...

Introduction: The cases of paragangliomas (PGLs) mimicking thyroid nodules were also reported in literature rarely. We will present a case of PGL (a carotid body tumor) that we initially evaluated as a thyroid nodule, and then diagnosed as a PGL.Case report: A 74-year-old woman was admitted due to a mass in the right side of neck growing rapidly within the last 1 month. Physical examination revealed a hard and painless mass with smooth surface, extending...

Introduction: Type two diabetes (T2DM), is the most common form of diabetes and known to be associated with low-grade inflammation. Since TLR-4 plays an important role in bacteriel recognition of lipopolysaccharide (LPS) and activation of proinflammatory pathways we aimed of to test whether TLR-4 gene polymorphism plays a protective role in the development of T2DM in a pilot Turkish population.Description of methods/design: Blood samples were collected f...

Riedel thyroiditis is a rare chronic inflammatory disease of the thyroid. It is characterized by replacement of normal parenchyma with dense fibrotic tissue. Peripheral tissues might also be affected and this may cause airway obstruction, dysphagia, recurrent laryngeal nerve palsy and hypoparathyroidism. We report a patient with toxic adenoma previously treated with radioactive iodine and histopathologically confirmed Riedel thyroiditis.Case: A 61 years ...

Introduction: Adrenal cysts are rare usually benign and asymptomatic. Histologically, they are classified as epithelial, endothelial, parasitic and pseudocysts. Although extremely rare and clinically more dramatic cystic adrenal carcinoma and cystic pheochromocytoma must be considered in the differential diagnosis of adrenal cysts. In this report, we presented a patient with a large cystic pheochromocytoma.Case report: A 30-year-old female patient admitt...

Introduction: Hypoglycemia is the most common endocrinological problem in emergency departments.Objective: To explore the causes of hypoglycemia in patients who were admitted to the emergency department with symptoms resembling hypoglycemia.Design: In our study, 225 hypoglycemia cases were evaluated from January 2000 to May 2008.Results: Of 225 hypoglycemia cases, 158 (70.2%) receiving treatment for diabetes ...

Hungry bone syndrome (HBS) is associated with recent parathyroid surgery. The Wolfram syndrome is characterised by diabetes insipidus, diabetes mellitus, optic atrophy and deafness. Other anomalies, such as renal outflow tracts and multiple neurological disorders may develop later. We present a Wolfram patient with tertiary hyperparathyroidism due to chronic renal failure associated with bilateral reterohidronephrosis who developed prolonged HBS after parathyroid adenomectomy....

Objective: Polycystic ovary syndrome (PCOS) is closely associated with insulin resistance (IR) and about 50–70% of women with PCOS have significantly increased IR. Our study was performed to determine the effects of metformin on IR indices with lean PCOS patients.Methods: Our study was a single center, randomized prospective study, approved by the local ethical committee. 53 patients with BMI <25 kg/m2 who had chronic anovulation and ...

Introduction: Multiple endocrine neoplasia type 2B (MEN 2B) is an aggressive disorder characterized by medullary thyroid cancer (MTC) and pheochromocytoma. Peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE is an effective new treatment for inoperable or metastatic neuroendocrine tumors (NETs). Hematologic problems, myelodysplastic syndrome or leukemia can be seen after alkylating agent and peptide receptor radionuclide therapy treatments. We present metastatic m...